Welcome to the Advanced Biofuels and Bioproducts Process Demonstration Unit. Part of the Lawrence Berkeley National Labs, we were established by the United States Department of Energy to help ramp up the bioeconomy.
DOE/EERE/BETO Programs Support
ABPDU provides a critical resource and direct support for several DOE/EERE/BETO programs and consortia
Five years in, the ABPDU has established more than 30 diverse partnershipsread more
This study explores the viability of streptomyces venezualae as a platform organism for large-scale cellulosic biofuel productionread more
What We Offer
With decades of industry and related experience in diverse areas of energy, materials, nanotechnology, molecular biology, biofuels, and biochemical process development and manufacturing, we are proud to have a talented, multi-disciplinary team that pools their significant expertise to forge new ground in bio-innovation.
Five years in, the ABPDU has established more than 30 diverse partnerships
Panorea Avdis, GO Biz’s Director, learned more about how the ABPDU can be a resource for young biosciences companies seeking to scale up operations
The American Institute of Chemical Engineers recognizes two ABPDU early-career researchers with honors to be bestowed at the 2017 AIChE Annual Meeting this fall
October 29 – November 1, 2017
October 29 – November 3, 2017
July 30 – August 3, 2017
Biosynthesis of highly branched short and long-chain hydrocarbons would enable production of biofuels with desirable and tunable properties, including compression ignition fuels with low freezing points. Polyketide synthase (PKS) pathways are a promising route towards production of such compounds; engineering of PKS pathways favors a native host- this work therefore focuses on development of Streptomyces venezualae ATCC 10712 as a platform organism. While S. venezualae is well characterized for industrial production of antibiotics, currently available protocols for high density fermentation make use of rich media and high-purity dextrose. The viability of Streptomyces as a platform organism for large-scale cellulosic biofuel production is therefore currently unknown.
This study focuses on the development of protocols for high density fed-batch fermentation of S. venezualae with cellulosic sugar feed in minimal medium to evaluate the viability of this strain as a production organism for fuels and commodity chemicals.
Mixed feedstocks can help reduce the risk associated with feedstock availability for bio-based production of fuels and chemicals. This study was performed to evaluate cellulosic hydrolysates for fermentation to biofuels and also probe the possibility of reducing nutrient concentration in the broth media.
The study demonstrated that mixed feedstocks can release 80 -100% of the sugar that is obtained from corn stover alone. A hundred percent of the released sugars from mixed feedstocks can be converted to ethanol. The study also showed that alkali pretreated mixed feedstock has higher ethanol yield but lower glucose yield compared to IL pretreated mixed feedstock due to inhibition of microbial growth by residual EmimAcetate. The same ethanol yield can be achieved with lower nutrient supplied but with longer fermentation time.
This paper presents two case studies on the scale-up and process integration of municipal solid waste conversion technology. In a partnership with Idaho National Labs, we successfully demonstrated 200-fold scale up of MSW blends IL acidolysis. We also developed an integrated process for ionic liquid based deconstruction technologies for MSW blends conversion. The scale up attempt will leverage the opportunity towards a cost-effective MSW blends conversion technology.
Under a DOE Work-For-Others agreement with FATER, ABPDU has been developing and validating an integrated waste-to-energy process. Key outcomes indicate that post-consumer absorbent hygiene products (AHPs) can be readily and economically converted — without using harsh or expensive pretreatment routes — to sugars and fuel intermediates.