Analytical Chemistry

Define, Improve, and Verify Your Innovation

Effective Scale-Up

Analytical chemistry delivers the information to define, improve, and verify technology innovation and enables robust process development. At ABPDU, we engage in continuous process improvement to enable the successful scaling of each unit operation as well as the integrated process.

Robust Validation

Knowing the critical importance of accurate data for process validation and improvement, at ABPDU we have exacting standards for data collection and analysis.  Among other things, we use extensive analytics to:

  • Understand the interaction between various feedstocks and deconstruction methodologies
  • Identify fermentation inhibitors
  • Obtain detailed recovery data for techno-economic modeling

Precise Quantification

Analytical chemistry is highly dependent on reproducible, robust, and reliable methods that provide precise quantification of the physio-chemical characteristics of a sample. Every project has challenges in sample handling, method selection, and process validation that are unique to that project.
Whenever possible we use protocols and techniques widely recognized by industry, but have the flexibility to adapt these protocols and develop methods customized to each project. Use of validation characteristics, such as accuracy, linearity, and precision ensures that the data provided is of the highest quality.

Our Equipment

Analytical Chemistry Options

Biomass Composition
We perform quantitative analyses of moisture, lignin, ash, glucan, and xylan in various biomass feedstocks per standard protocols. Through HPLC, we also measure sugar and degradation product concentrations in biomass hydrolysates.
Material Physical Properties
We use rheology and energy density methodologies to understand the physio and chemical properties of starting materials to support operational planning and process design from scale up to commercialization.
Protein Characterization
We carry out qualitative and quantitative analyses of proteins and enzymes. Our analysis capabilities include SDS-PAGE, protein content, and microplate activity assays.

Related Papers & Publications

 

Predictive Modeling Can De-Risk Bio-based Production

Technologies developed to generate bio-based products are based on single feedstock types. While this approach is applicable for corn stover in the MidWest, for states such as California, with abundant but diverse feedstocks, technologies should be developed to accommodate multiple feedstock input to a single biorefinery.