Lawrence Berkeley National Laboratory (Berkeley Lab) will partner with four clean energy small businesses to accelerate the commercialization of their innovative bioenergy, buildings and vehicle technologies as part of the Small Business Vouchers (SBV) pilot launched in July 2015 by the U.S. Department of Energy (DOE). One of those companies is Lygos, Inc., which has partnered with the Advanced Biofuels Process Demonstration Unit (ABPDU) in the past to achieve pilot-scale production of malonic acid from sugar. Lygos will conduct the necessary testing at the APBDU to overcome current barriers to scale-up, and then move production to the large-scale fermenters at DOE’s National Renewable Energy Laboratory.